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company overview

X4 Pharmaceuticals is a company focused on improving the lives of people with rare hematology diseases by developing and commercializing innovative therapies in areas with significant unmet needs. Leveraging expertise in diseases of the immune system and CXCR4 biology, X4 has successfully developed mavorixafor, an orally available CXCR4 antagonist that is commercially available in the U.S. as XOLREMDI® in its first indication. The Company is currently conducting a global, pivotal Phase 3 clinical trial (4WARD) evaluating mavorixafor in chronic neutropenic disorders. The U.S. FDA has granted Fast Track designation to mavorixafor for the treatment of chronic neutropenia. X4 is headquartered in Boston, Massachusetts.

Presentations

EHA 2025: Evaluating the Safety and Efficacy of Mavorixafor, an Oral CXCR4 Antagonist, in Participants with Primary Chronic Neutropenic Disorders: Results from the Phase 2 Study
EHA 2025: Mavorixafor, an Oral CXCR4 Antagonist, Allows for Granulocyte-Colony Stimulating Factor Dose De-Escalation in Phase 2 Trial Participants with Primary Chronic Neutropenia
XOLREMDI™ (mavorixafor) FDA Approval Conference Call and Webcast Presentation
ASH 2023: Mavorixafor for Patients with Chronic Neutropenic Disorders Treated with G-CSF